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Update Date: [2022-09-30]

Publication The Immunity Program Establishment and Vicissitudes of the Maternal Antibody Titer of Pigs of the Multi-efficacy Combined Bacterin of Bordetella, Pasteurella, Actinobacillus, E.coli Antigens for Swine

Reportno.

AHRI report No.29

Topic

The Immunity Program Establishment and Vicissitudes of the Maternal Antibody Titer of Pigs of the Multi-efficacy Combined Bacterin of Bordetella, Pasteurella, Actinobacillus, E.coli Antigens for Swine

Department

1. Taiwan Provincial Research Institute for Animal Health. 
2. Yunlin Hsien Livestock Disease Control Center.

Author C. Chen 1, C.C. Lu1, J.C. Lai', H.J. K'o' LP. Chan', C.J. Li2 and G.S. Tsai2 
Summary

The multi-efficacy bacterin containing Bordetella bronchiseptica (B.b), Pasteurella multocida (P.m.), Actinobacillus (Haemophilus) pleuropneumoniae (A.p. or H. p.) and Escherichia coli (E. coli) was produced and tried out. Two groups of sow administ-ered twice with 3 ml and 5 ml bacterin were compared. The geometric mean titer of the maternal antibody in 4-day-old suckling piglets against B.b. were higher in the 5 ml group ( 1: 6,450-1: 7,068) than in the 3 ml group ( 1: 2, 791-1: 3,446). 

In the field trials, 4 7 sows were initially administered with 3 ml of the bacterin and boostered with 5 ml after two weeks. The results indicated that 97.9 % of the sows showed anti-B.b. titer over 1: 1,280 and 93.6 % of their offsprings also showed the same results. 
As to the vicissitudes of the maternal antibody titer of the 94 piglets from the sows vaccinated in the field trial, the geometric mean titers at the ages of 4 day , 4 week , 8 week, 10 week and 12 weeks were 1 : 3,594, 1 : 1,036, 1 : 250, 1: 55 and 1: 35, respee tively. The results suggested that vaccinating piglets at the age of 8 to 10 weeks with 2 to 3 ml intramuscular administration may produce protective immunity. 

Keyword

Bordetel/a bronchiseptica, Pasteurel/a multocida, Actinobacillus pleuropneumoniae, Escherichia coli, Multi-efficacy combination bacterin.

 


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