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Update Date: [2022-09-23]

Publication Cutaneous Delayed-type Hypersensitive Reaction as a Diagnostic Test for Pseudorabies Virus Infection in Swine

Reportno.

AHRI report No.19

Topic

Cutaneous Delayed-type Hypersensitive Reaction as a Diagnostic Test for Pseudorabies Virus Infection in Swine

Department

Taiwan Animal Health Research Institute

Author

M. H. Jong and S S Lai

Summary

Severe reaction was seen by subcutaneous injection with concentrated and heat-inactivated PrV antigen into lower eyelid of swine. This reaction was verified as d-elayedtype hypersensitive reaction by histopathological changes. Nonexposed control pigs did not react to the viral and cellular antigens at all. The correlation among serum neutralization, microimmunodiffusion, and skin tests was analysed. The results indicated that the sensitivities of the latter two tests were pretty high and similar to each other. The antigens obtained by treating the infected cells with proteolytic enzyme were suitable for microimmunodiffusion test. 

Keyword

Cutaneous Delayed-type Hypersensitive Reaction; Diagnostic Test; Pseudorabies Virus

 


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