| Topic |
Development and Field Application of Bordetella, Pasteurella, Actinobacillus, Escherichia coli, Salmonella and Pseudorabies virus lnactivated Combine
|
| Author |
CHEN Ching,1* M. H. Jong, 1 I. P. Chan, 1 C. C. Lu, 1 T. F. Chiou,' J. S. Lai,1 H.J. Ko, 1 C. J. Li,2 T. K. Li,2 F. M. Li,2 Y. C. Wu,2 K. T. Wu,2 C. C. Kao,2 and Q. S. Tsai.2 |
| Summary |
The sows immunized with poly-valent vaccine, adjuvanted with either aluminum hydroxide gel or oil adjuvant, developed antibody titers ranged from 1 : 5,120 to 1 : 20,480 against Bordetella bronchiseptia ( B.b) antigen as determinde by using tube agglutination test, The passive antibody titers were 1 : 1,413 to 1 : 4,035 in their 4 days old piglets. As the piglets grew older, the antibody titers decreased.
In the laboratory, the antibody titer developed against pseudorabies (Pr.) antigen from the serum and colostrum of the sows after vaccination varied from 1 : 11 to 1 : 256 by serum neutralization test. The passive antibody titers were 1 : 8.4 to 1 : 26.7 and 1 : 3.6 to 1 : 7.4 for their 4-day and 4-week old piglets, respectively. After 8 and 12 weeks old, those values dropped below 1 : 2.
In the field trial, the serum antibody titers against B.b for the vaccinated sows ranged from 1 : 130 to 1 : 160 in prevaccination and 1 : 3,566 to 1 : 3,680 on 3-4 days after farrowing. The geometric mean titer ( GMT ) of the passive immune titer measured 1 : 1,810 to 1 : 2,168 for their 3-4 days old piglets.The GMT antibody titer against Pr. antigen of sows after vaccination also increased distinguishably. For their 4-day and 4-week old piglets, the passive antibody titer varied from 1 : 277 to 1 : 342 and 1 : 162 to 1 : 167, respectively. Based on these experimental results, the increase in the immune antibody titers were fairly satisfactory.
|
| Keyword |
Bordetella bronchiseptica, Pasteurella multocida, Actinobacillus pleuropneumoniae, Escherichia coli, Salmonella choleraesuis, Pseudorabies virus, Combination vaccine
|