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Update Date: [2022-10-11]

Development of Multivalent Immunoglobulin Y for Waterfowl's Viral Diseases

Reportno. AHRI report No.48
Topic

Development of Multivalent Immunoglobulin Y for Waterfowl's Viral Diseases

Department Animal Health Research Institute, Council of Agriculture, Executive Yuan
Author YH Shih*, CH Tseng, AP Hus, TS Huang
Summary This purpose of this study was to develop duck hepatitis virus and waterfowl parvovirus yolk antibodies for the treatment of these viral diseases in young ducklings. The safety and effectiveness of the duck hepatitis virus IgY (DHAV-1 IgY) and waterfowl parvovirus IgY were performed by two companies.  The results showed DHAV-1 IgY injections could induce good protection against duck hepatitis virus (DHAV-1) if the neutralization antibody titers were ≥1,000, while the waterfowl parvovirus yolk antibody titers could induce good protection against waterfowl parvovirus if the neutralization antibody titers were ≥3,000 within 10 days after injection.  This indicates that the yolk neutralization antibodies of the IgY should be ≥1, 000 or ≥3,000 for duck hepatitis virus and waterfowl parvovirus, respectively, for treatment against these two viral diseases.  These IgY could be used for passive protection against duck hepatitis virus and waterfowl parvovirus during outbreak or prevention according to waterfowl industry requires. 
Keyword duck hepatitis virus, water fowl parvovirus, immunoglobulin Y. 

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