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Update Date: [2022-10-05]

Publication Simultaneous Determination of Nineteen Synthetic Antibacteial Drugs

Reportno.

AHRI report No.33

Topic

Simultaneous Determination of Nineteen Synthetic Antibacteial Drugs

Department

Residuls in Domestic and Fishery Products Taiwan Animal Health Research Institute. 

Author M. Y. Kueo*, S. Y. Lin, K. M. Lin, M. C. Lin, and Y. F. Liu
Summary

Simultaneous determination of trimethoprim ( TMP ) , ormethoprim ( OMP ) , 
olaquindox ( ODX) , clopidol ( CLP ) , oxolinic Acid ( OXA) , piromidic acid ( PMA) , carbadox ( CDX ) , morantel citrate ( MRT ) , difurazone ( DFZ ) , nicarbazine ( NCZ ) , thiophenicol ( TPC ) , sulfamerazine ( SMR ) , sulfamethazine ( SMT ) , sulfamonome-thoxine ( SMM ) , sulfadimethoxine ( SDM ) ' sulfaquinoxaline ( SQX ) , pyrimethamine ( PYR ) , nalidixic acid ( NAA ) & furazolidone ( FZD ) residues in meat by high performance liquid chromatography with photo diode array, Good linear effect could be obtained when 0.3125 ~ 10 ppm standards chromatographied in. TSK Gel ODS-80 TM with 80 % actonitrile and 0.1 % phosphoric acid by linear solvent program. Recoveries of most spiked samples could be up to 80 % after extracted by acetonitrile and purified by hexane. Recoveries of SDM , SQX and PYR were 55.5~ 62.6 % , ODX and DFZ were 17.4 % and 14.2 % ; however, CLP was uncalculable, NCZ was undetectable. 

Keyword

High performance liquide chromatography , Photo diode array detector , Synthetic Antibimicrobial drugs

 


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