ChingChen1, C. C. Lu', S. T. Lin', T. G. Chang', J. H. Li1, Y. H. Yang', T. H. Fuh1, and H.K. Shieh2
Two hundred and fourteen sera samples from two groups of rabbits were subjected to determination of atrophic rhinitis antibody by agglutination test. Fourty-eight (44%) out of 109 from group A were positive (1: 10) in AR antibody, while 31 out of 105 from group B were positive (29 .5%). The total positive rate was 36 .9% (79/214).
The distribution of the antibody levels were 24 samples (I 1.2%) for 1:40, 17 samples
(7.9%) for 1:20, 16 (7.5%) for 1:80, II (5.1%) for 1:10, and 11 (5.1%) for 1:160 or higher.
Fifteen random samples and 30 samples from rabbits with clinical signs (sneeze etc.) were collected by use of nasal swabs, and cultured for isolation of Bordetel/a bronchiseptica. Sera were also collected from the same rabbits for AR antibody detection. The bacteria (B. bronchiseptica) were isolated from 10 out of the 15 random samples and 29 out of the 30 samples (rabbits with clinical signs), while the antibody positive rate was 40% (6/15) and 86.7% (26/30), respectively. The bacterial isolates did produce dermonecrotic toxin when demon-strated on guinea-pigs.
The results indicated that the rabbit population in Taiwan was highly contaminated with Bordetella bronchiseptica, i.e. Atrophic rhinitis.