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Update Date: [2022-10-06]

Publication Development and Application of Simultaneous Determination of Synthetic Antimicrobial Drugs in Chicken Feeds


Reportno.

AHRI report No.35
Topic

Development and Application of Simultaneous Determination of Synthetic Antimicrobial Drugs in Chicken Feeds 
Department

The Branch Institute of Animal Drugs Inspection , National Institute For Animal Health , Council of Agriculture ,  The Executive Yuan
Author K. M. Lin , M. C. Liu , M. Y. Kueo , S. Y. Lin , S. C. Yang
Summary

A high-performance liquid chromatography (HPLC) method for simultaneous determination of sulfamethazine (SMT), sulfamerazine (SMR), sulfathiazole (STZ), sulfamonomethoxine (SMM), sulfadimethoxine (SDM), sulfaquinoxaline (SQX), oxolinic acid (OXA), piromidic acid (PMA), and nalidixic acid (NAA) in chicken feeds was developed. The feed samples spiked with synthetic antimicrobial drugs at levels of 1.25, 5 and 20 ppm. respectively, were analysed.  The average recovery rates of OXA , FLU and NAA were 96.6% , 96.1.0% and 96.3%, respectively.
The average recovery rates of SMR , SMT , SDM , and SQX were 41.3% , 69.0% , 63.0% and 83%, respectively.
Keyword

Feed, Synthetic antimicrobial drug, Simultaneous determination