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Update Date: [2022-09-29]

Publication Chromosome Aberration Test of Feed Additives in Chinese Hamster CHO-Kl Cell


Reportno.

AHRI report No.28

Topic

Chromosome Aberration Test of Feed Additives in Chinese Hamster CHO-Kl Cell

Department

Taiwan Provincial Research Institute for Animal Healt

Author S.Y. Lin*, S.C. Lee and S.Y. Chiu 
Summary

Chinese hamster CHO-Kl cell showed cytotoxity when cultured in 1000 and 333 ppm of carbadox. Some of these cells died and mitotic cell could hardly be observed. However, the cells showed diploid chromosomes but no aberration when they were exposed to 111, 37 and 12 ppm of carbadox. Olaquindox induced polyploids only. Both furazolidone and nitrovin demostrated more cytotoxic than carbadox and ola-quindox but did not induced chromosome aberration. 

Keyword

Chinese Hamster;CHO-Kl Cell

 


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