Pseudorabies (Pr.) inactivated vaccines were assayed with mice, guinea pigs, rabbits and pigs. The results showed that vaccine having higher protective titer in rabbits could also have good protective titer in mice or guinea pigs. The model of guinea pigs vaccinated twice with higher dose group was regarded as the best one to replace rabbit model.
The antibody response in swine for Pr. vaccines was not good enough, it meant that vaccine quality should be improved.