Two thouand and ten serum samples were collected from 67 farms in the end of January and October, respectively. The serological survey were performed for BEF, Akabane disease, Ibaraki disease and Chuzan disease to evaluate the strategies of vaccination and alarm the farms to boosting. Rapid diagnosis the disease by RT-PCR, and the mean time isolation the virus by BHK cell, proceeding analysis the virus sequences is the best way to control the disease. We expect to reduce infection rate and morbidity by 0.5%/year and economic losses caused by fever, milk production, abortion, stillbirth and dysplasia after this program was