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Update Date: [2022-09-20]

Publication Studies on the Lyophilization of Bovine Viral Diarrhea Virus (BVDV)



AHRI report No.13


Studies on the Lyophilization of Bovine Viral Diarrhea Virus (BVDV) 

Department Taiwan Animal Health Research Institute
Author P. P. Liou T. S. Huang 

Lyophilized bovine viral diarrhea virus (BVDV) vaccines were Prepared using four recommended stabilizing mediums., !0%NZ-Amine, !%Albumin, 2 %Peptone and 0.3% PVP (Polyvinyl Pyrrolidone) . These four vaccines were compared with each other relative to their suitability for (I) . Appearance and solubility characteristics ; (2) . ma-intaining virus titers during lyophilization ; (3) . quality of restoration ; C 4) . maintaing stable of virus titers and antigenicity under various storage temperatures. 
From the results, it may be possible to prepare a more satisfactory vaccine with a medium prepared from components of 0.3%PVP. This may be worthy of investigation at a later date. 


Lyophi]ization Bovine Viral Diarrhea Virus BVDV


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