| Summary |
In 2002, Sagiyama virus was first isolated from pigs located in Miao-Li County, Taiwan. During that year, 586 serum samples of marketing pigs were collected from 11 counties and tested by serum neutralization test. The positive rate of serum antibodies against sagiyama virus was 51%（296/586）. In a trial, 9 pigs aged at 12-week old without antibodies against sagiyama virus were divided into two groups. The first group consisted of 7 pigs were inoculated intramuscularly with sagiyama virus suspension, respectively. The second group consisted of 2 pigs were uninfected and housed together with the first group for studying the transmission. During a 2-week observation, all the pigs did not show significant clinical symptoms and special pathological lesions when those infected pigs was sacrificed on the 2,3,5,7 and 10 days post inoculation, respectively. Although the infected pigs developed viremia and shedding infectious virus particles from secretion and excretion for the first 1-2 days post inoculation, the two contact control pigs remained negative in virus isolation and antibody response through the 8-week study.
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