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Update Date: [2022-09-19]

Publication Studies on Induced Resistance of Streptococcus A galactiae Against Penicillin and Streptomycin


AHRI report No.10


Studies on Induced Resistance of Streptococcus A galactiae Against Penicillin and Streptomycin

Department Taiwan Animal Health Research Institute
Author Chen Shou-She, Chiu Tsau-chi, Lin Kuan-Jung

Two hundred and thirty five strains of Streptococci which were isoleted from various area of Taiwan Prouince. Streptococcus agalactiae was determinated firstly by means of CAMP test and biological methods. 
Twenty antibiotic sensitive Streptococcus agalactiae with stable charracter were then selected by means of antibiotic sensitivity test. The abovementioned strains were passaged in Trypticase broth in which containing either Penicillin or Streptomycin. The YIIC was checked every five passages by means of Tube Dilution Method. 
The results indicated that resistance to ponicillin or streptomycin could be induced in the broth containing the antibiotics. Resistance was induced slowly in penicillin and the induced resistance only in about 10 fold (range 2-50). The resistance to streptomycin was induced rapidly. In first five passages, Streptococcus agalactiae increased its resistance to streptomycin by fiye fold in everage (range 1-25). then up to 50 fold (range 10-150) Changes in biological charracter and morphorlogy had also been observed in induced antibiotic strains. 


Sixeptooxcus ; Penicillin; Sireptonycin

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