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Two tuberculin tests were performed in 12 artificially inoculated milk goats; 10 milk goats were inoculated with killed Corynebacterium pseudotuberculosis treated by 0.3% formalin and 2 were inoculated with 2ml live bacteria (lxlO C.F. U/ml).
The increases in skin thickness from 12 artificially inoculated milk goats were compared with those from 3 naturally infected milk goats by statistical t-test. Very significant difference in increase in skin thickness was found between 3 natural infections and 10 artificial killed bacteria inoculations (P < 0.01 ), and the diff-erence between 10 milk goats inoculated with killed bacteria and 2 inoculated with live bacteria at 18th week postinoculation was also significant (P<0.05).
The results indicated the interference of tuberculin test from 3_ naturally infected milk goats and 2 infected with live bacteria was stronger than that from the 10 inoculated with killed bacteria.
The increase in skin thickness of tuberculin test in 2 milk goats, free from Mycobacterium infection, inoculated with killed Corynebacterium pseudotubeculosis indicated that only whole cells of Corynebacterium pseudotuberculosis could interfer tuberculin test.
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