Analysis of Characteristics, Virulence, Phylogenesis, and Antimicrobial Resistance of Respiratory Tract Bacterial Pathogens Isolated from Diseased Cattle and Goats in Taiwan

NL Kuan*,C Tu

Animal Health Research institute, Council of Agriculture, Executive Yuan

Abstract

Pathogenic bacteria in the ruminant respiratory system usually are considered as opportunists; though bacterial infections sometimes cause severe clinical signs and economic losses. There are only a few studies and investigations about this topic in Taiwan in recent years and the impact of bacterial infections on ruminants may be underestimated. In this study, 98 isolates were recovered from 61 clinical cases from December 2009 to December 2017. Thirty-seven isolates of Pasteurella multocida,18 isolates of Mannheimia haemolytica, 10 isolates of Moraxella sp. and 5 isolates of Bibersteinia trehalosi were included. The main serotype of Pasteurella multocida was type D and the secondary was type A. According to MLST analysis, the Pasteurella multocida isolates belonged to ST79 and 5 new ST, and Mannheimia haemolytica belonged to ST1, ST2, ST16, ST21, ST28, and 4 new ST. Most of the isolates were susceptible to amoxicillin/clavulanic acid, ceftiofur, florfenicol, and enrofloxacin.

Keywords: Pasteurella multocida, Mannheimia haemolytica,multilocus sequence typing (MLST), antimicrobial resistance