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Seminar 933

Date:2022-07-29 Update:2022-07-29

Establishment of a safety and efficacy method for evaluati ng subunit E2 vaccine against classical swine fever in pregnant sows

Jen Huan Tsai


Cl assical s wine fever is a highly contagious septicemia caused by the infection of classical swine fever virus w hich is an RNA virus belonging to the genus Pestivirus of the family Flaviviridae Due to transplacenta transmission of the vir us , it is very important for vaccine efficacy evaluation in pregnant sows and piglets p rotection Therefore, w e established a vaccination and challenge test in pregnant sows as a method to assess the safety and efficacy of the subunit E2 vaccine.


Quality Control Inspection of Biologics During 2020-2021

Cheng-chu Hsieh


In 1988, we established a pharmaceutical factory that complied with the GMP standard requirements at the Animal Health Research Institute (AHRI). The main tasks of the biological products division are the production, development, storage and supply of vaccines and diagnostic reagents. AHRI currently possesses 21 manufacturing licenses for various biological animal products including Newcastle disease hemaggluutination antigen, pullorum disease antigen, bovine ephemeral fever inactivated vaccine, hog cholera tissue culture live vaccine, waterfowl parvovirus live vaccine, goat pox attenuated live vaccine, and Riemerella anatipestifer (RA) inactivated trivalent bacterins (serotpye 1, 2 and 6). An analysis of data from 2020-2021 showed that more than 10 different batches of biological preparations are manufactured each year. Each batch was qualified for quality control and national inspection, providing for domestic epidemic prevention and diagnosis.

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