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Update Date: [2013-11-05]

NO.: 20

AHRI report No.20


Studies on Escherichia coli Originated from Diarrhea of Suckling Piglets in Taiwan


1.Taiwan Animal Health Research Institue
2.Sc&d of Veerinary Mdicine and Animal Science. Kitasato Univexsity. Jaren egrimen 3. Research Cent for Vetinary Science. Kitasato Institutu JAPAN

Author C. (Thenl ; Tsuneo KUME 2Masami HUMA3Shiro TSUBAKI 2;Keitaro ANDO 2-,J1roSASAHARA2
Escherichia coli, isolated from the suckling piglets with diarrhea, were used for vaccine production. The immunity is discussed as follows: The pregnant sows were immunized with the enterotoxins (LT, ST) and vero cytotoxin vaccine or the pili(K88, K99, 987p) vaccine. After farro wing, the suckling piglets were orally challengaed with bacterial suspension to detect their protection ability. Besides, several tests were performed: agar gel immunodiffusion tests, to detect anti-pili antibodues. The results

of the experiment indicated that the sows acquired immunity from the enterotoxinxs or the pili vaccine, and their suckling piglets obtained passive immunity via the colostrum. However, the cross immunization could not be obtained in these two types of vaccines. In practical appltcation, it is essential for vaccines to be able to produce enterotoxins and pili strains. By virue of the application of the application of vaccines, the Immunizatin on both sows and their suckling piglets was considered to be possible and was highly thought of.


Escherichia cxAiflarrhea; suclding piglets