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Update Date: [2013-10-31]

Plan Year: 2005
    We have established the optimal conditions to large scale culture the Bordetella bronchiseptica and Actinobacillus pleuropneumonia by using broth medium in shaking incubator and fermentor.  These techniques will improve the defects by culturing in agar, which is laborous in large scale production.  The high titer of antigens and economical bacterial vaccines were produced eventually.