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Update Date: [2013-11-05]

NO.: 20

AHRI report No.20


Pathological Changes in Piglets Inoculated Intranasally With TNL Strain of Pseudorabies Virus


Taiwan Animal Health Research Institute


S.Y. Yang;N.J. Li;J.S. Y.H. Yang;S.S. Lai


Y. Yang;N.J. Li;J.S. Y.H. Yang;S.S. Lai
Summary:Nonsuppurative menlingoencephalomyelitis with focal or diffuse gliosis, lymphocytic perivascular cuffing, neurophagia, and focal necrosis of lung were produced in piglets inoculated intransaally with 1 O”8.6 TCID5O TNL strain of pseudorabies virus (Pry). Eosinophilic intranuclear inclusion bodies were easily found in the necrotic areas of lung, but not found in the brain and spinal cord. The transmission of PrV from trigeminal and glossopharyngeal nerve to brain seemed more rapid than that from olfactory nerve. The pons was preferred for histopathologic examination. Intranasal inoculation of high dose of Pry could induce focal necrosis in visceral organs.


Pseudorabies Virus pseudorabies virus PrV