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Publication DEVELOPMENT AND FIELD APPLICATION OF DIAGNOSTIC ANTIGEN AND AN INACT...  

Update Date: [2013-11-05]

NO.: 21
 
Reportno.

AHRI report No.21

Topic

DEVELOPMENT AND FIELD APPLICATION OF DIAGNOSTIC ANTIGEN AND AN INACTIVATIVE VACCINE AGAINST EGG-DROP SYNDROM-76

Department

1.Taiwan Asthnal Health Researdi Institute
2.Council of Agriculture. Eaoutive Yuan

Author Y.S. Lu,1D.F. Linl;HJ. TsallC.Leel;Y.L Leel$.Y,Chiul;Y.H. Lieu2$.t H1
Summary

The preparation of the hemagglutinatir*g antigen for diagnc€is of Egg-Drop Syndrome4 976 (EDS-7 was desC&CC1. The antigen rnultip&al in duck embryo was inactivai th 0.2% fonnalin and then was lyphophulil. The lypliophiliI antigen oould maintain its HA tine at least one year in 4?

Fromolii in&invatl varxine in oil adjuvant and in aluminum hydroxyl gel were gep3xel, It is found that both kinds of inactivated vathnes were safety and effective in the evoking of the antibody against EDS-76. It is also suggestui that the immnunogenidty of the oil vathne was great The mean HI titer of antibody against EDS-76 in the inoculatl chicken was above 1:20 at two weeks poet inczulation. The Hltiterlastelatleastfcyr6rnonths.

Large scale application of the inactivated vaccine in oil adjuvant against EDS-76 was carried out. Total of 40,%A) breeder chicken and 14,040 dirt were inoculated and gcxd gottion against EDS-76 infection was achieved.

Keyword

hemagglutinating anti yphophiliz5d antigenromolil inactivated vaccine