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Sequence Analysis of Avian Paramyxoviruses in Taiwan  

Update Date: [2013-11-14]

AHRI report No.47
Sequence Analysis of Avian Paramyxoviruses in Taiwan
1 National Institute for Animal Health, Council of Agriculture, Executive Yuan
2 School of Veterinary Medicine, National Taiwan University
YP Liu1,2, MC Cheng1, MS Lee1, LH Chen1, SH Lee1, HJ Tsai 1,2,*
Avian paramyxovirus serotype 1 (Newcastle disease, ND) is most commonly isolated serotype in Taiwan; however the information about the distribution of all APMV serotype 1-9 in domestic poultry, wild birds, imported birds and pet birds is very limited. This study used molecular techniques to determine serotypes and the distribution of these in Taiwan. Fifty-four APMV isolates were characterized to be 15 APMV-1, 1 APMV-2, 17 APMV-4, 8 APMV-6 and 13 APMV-7, respectively. The complete genome sequence of APMV-7 strain AHRI-33 was determined, and this strain showed only 36~73% of amino acid identity with the reference APMV-7 strains in GenBank. Our results provide evidence for the existence of subgroups within a given serotype. The results of the phylogenetic analysis of fusion proteins placed 15 APMV-1 strains into five genotypes- I, II, VI, VII and one additional novel genotype. The present study suggests that in addition to ND, there are at least four more serotypes of APMVs circulating in poultry and wild birds in Taiwan. This information may prove be useful for future epidemiological studies of APMV isolates from Taiwan.
Avian paramyxovirus, Newcastle disease