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Publication Histopathologic Studies on the Pig Experimentally Infected by Wild S...  

Update Date: [2013-11-13]

NO.: 33

AHRI report No.33


Histopathologic Studies on the Pig Experimentally Infected by Wild Strain of Hog Cholera Virus 



Animal Health Research listitit C<uncil of Agriculture

Author S,H Lee*;M,H Jong;’LLL1n;LJ. Ting, SCYang

Secondary SPF pigs with 5 weeks of age were infected experirrienlly with 2 isolates of hog cholera virus (HCV) obtained from 2 outbreaks ketween 1993— 1994 via oronasal rout Sirni]argcoss lesion to the rerent cases, stuck as spleen infarction and rripheral hemorrhage of lymph nccles were not really seen. Histopathological changes were charactethed by depletion of nature lymphocyt and proliferation of reticular endothelial cells. Nonsuppuxative encephalitis was not so evident as that causer! by other viral diseases and not distinguishable from that caused by septicemia uniiuaiy salinonellosis. HCV could ke rerovered from the tissnes bring tested of all pigs scones r later. However, tonsil, meseatric lymph noc and inguinal lymph nc& were the rget where the virus could ke isolatl earlistly and consistently by cell culture and PCR ecimique. Diphasic fehule reaction, a typical reaction of LPC-(3iina stain, was not okcerveiintherabbits infectelby94-4 andS59stains. Baselonthefindiizgsof histohtology, virus isolatin PCR and rabbit repc>nse were realized that these 2 field viruses axe not ‘nrulent stain or LPC-china stain.


Hog Cholera flj:eriinentally infact&$istopathologic finding.