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Publication Chromosome Aberration Test of Feed Additives in Chinese Hamster CHO-...  

Update Date: [2013-11-11]

NO.: 28
 
Reportno.

AHRI report No.28

Topic

Chromosome Aberration Test of Feed Additives in Chinese Hamster CHO-Kl Cell

Department

Taiwan Animal Health Research Institute

Author S.Y.Lin. LinFS.C. LeeFS.Y. Chiu
Summary

Chinese hamster CHO-Ki cell showed cytotoxitv when cultured in 1000 and 333 ppm of carbadox. Some of these cells died and mitotic cell could hardly be observed. However, the cells showed diploid chromosomes but no aberration
when they were exposed to 111, 37 and 12 ppm of carbadox. Olaquindox induced polvploids only. Both furazolidone and nitrovin demostrated more cytotoxic than carbadox and olaquindox but did not induced chromosome aberration

Keyword

Chromosome Aberration TestFChinese HamsteqFcytotoxity