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Publication Efficacy of the gE-deleted Pseudorabies Inactivated Vaccine  

Update Date: [2013-11-13]

NO.: 31
 
Reportno.

AHRI report No.31

Topic

Efficacy of the gE-deleted Pseudorabies Inactivated Vaccine

 

Department

2Depaxtnent of Veterinary Mdicine, National Chung-Hsing University 3.Yunlin Hsien Livestcck Disease Control Center

Author MH. Jor4*1SH Lee lLJ. Ting 1$.N, Wu 1;LP. Chanl;tJ. Chang2$3.S. Tsai 3C.C. be3
Summary

Proegative ability of the gE and TK double gene-deleted R23 stain cc’nstrni from iccal isolate and natural gE gene-deleted Bartha stain of p6eudcuabies virus both in PK cell line was satisfied, Immune goeDtive eff’nDy of these two inactivated vaccines in rabbit was oo’rnparable with that ofS-38 field stain and irnportl gE genedeleted N and SB v&xdines. Protective dc€age in rabbits induct! by all of them ould
ss the test of national drug assay. The neutralizing antibcdies of sa:ondary SPF pigs
with 5—? weeks of age elicited by the lccal gene-deleted R23 inactivated vaccine were slightly lower then thcGe by other vaccines. However, it proatl the pigs as gccd as the other vaccines when evaluated by mean fever and virus shalding days points of view.

 

Keyword

PseudcnbiegGene-deletion;Inactivatoi vaccine.