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Publication Efficacy Evaluations of the Inactivated Swine Vesicular Disease Vacc...  

Update Date: [2013-11-13]

NO.: 36
 
Reportno.

AHRI report No.36

Topic

Efficacy Evaluations of the Inactivated Swine Vesicular Disease Vaccine

 

Department

Animal Health Reseaxdi Institute, Council of Agriculture, Firutiw Yuan

Author Tbig. Lu- Jen , t F, Chiou, M. H. JongandC Chen
Summary

Swine vesicular disease (SVD) virus, TN1 strain, was grown in ES K cells and reaching a titer of 108.1 TC1D5Cnl. The SVD waterkAlkater (W,O/W) vaccine was prepared from the virus inactivated with binary ethylenirnine (BED and emulsified with Monnide LSA2CIS. Ten srthfic pathogen he (SPF) pigs at 5-7 weeks of age were used to evaluate the inactivated SVD vaccine. Result revealed that the SVD vaccine elicited gxd titers of neutralizing antibodies ranging from 3.79 to 3.88 log10 aft two thne vaccinations with a four-week interval. This vaccine also conferred protection fc’r pigs post challenge however the control pigs without receiving vaccination developol visible lesions on the snout fcot and dewdaw areas.

 

Keyword

Swine vesicular disease, Inactivated vaccine, Water/oilAvater vaccine, Sthfic mthonn free pin