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Publication Feasibility of the hog cholera vaccination by intranasal or oral rou...  

Update Date: [2013-11-13]

NO.: 30
 
Reportno.

AHRI report No.30

Topic

Feasibility of the hog cholera vaccination by intranasal or oral route
 

Department

Taiwan Animal Health Reseastli Institut

Author T.S. Huang, S.Y. CHem, Y.L. Lin, C.H. Pan, S.H. Le, Y.H. Yang and I.C, Pan
Summary

Forty-seven piglet, fantwei and fed by gilt and sews, were divided into 6 groups and inocuiaJ with a dose of LPC vaccine either by intranasal or oral rout at 2 to 7weks ofage, xespatively, Piglet each incculatd by the oral rout was fed with 4 ml of bvine olostnira just can to oral thxulaton. All pigs were challenge inccilatl withAlJJhogcholeaviniletntvinis by LM.at l0webokiThexesultshowedthat only 1’7piglets (about 36%) were refractory to the challenge. While another 34 piglet, from gilt and sews, were divided into 4 groups and incxdati with a dose of LPC v&xinebyintranasalroutorfedwithknvineottwmjustpsiortoincculation, at2to S weeks of age; reapotively. All 34 pigs were challenger! by Ut on.ct infection, at 10 web of age. The result shower! that only 2 piglet (abut 5.8%) were refractory to the o,ntact infection challenge. Either the routs of incculation or the age; the nun*er of fan-owing of pigs seems no influence on immune response. The poor mucc€al immunity jxokably keause the stimulation of a immune response by a dose of LPC vaxine was not cx>nsistily esblisheJ. Forty-seven piglet, &rrn and fed by gilt and sews, were v&xinatd by I.M. at 326 weeks ofageunclerthecuntntvathnation gogran. Aft snd vaccination, 31 pigs were challenge inoc’u1ai with AID ‘ins by LM., and another 16 pigs were refractory ei&r to the LM. incculation challenge or conct infection. However, the current vaotination gogi-am should It tstez! and revised for the conminatd herds for eliminating the low ind&nce of hog cholera.

Keyword

Hog chole, Mwxeal immunition