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Publication CASE STUDY ON A DOG CONCURRENT INFECTED WITH CANINE PARVOVIRUS AND T...  

Update Date: [2013-11-11]

NO.: 28
 
Reportno.

AHRI report No.28

Topic

CASE STUDY ON A DOG CONCURRENT INFECTED WITH CANINE PARVOVIRUS AND TYPE2 ADENOVIRUS

Department

Taiwan Animal Health Research Institute

Author Y.S. LuflLC. ChengFD.T. LinFSX LeeFYK. LiaoFYi. LeeFM.3. Author Kwang4FD.F. LinFH.J. Tsai
Summary

In February of 1988, a four-month-old female Akita-breed dog was submitted to our Lab for diagnosis. The dog had fever, anorexia, and vomiting, bloody diarrhea and died at 5 days after onset of the disease. Gross lesions included congestion and inflammation on mucosa of small intestine, stomach, and bladder. Microscopic lesions included severe atrophy of vilii, swollen and necro sis of crvpts of small intestine.

wo viruses were isolated by inoculating faces and intestinal contents onto Crandell feline kidney cell line and Madin-Darby canine kidney cell line. These viruses were identified as a canine parvovoirus and a type 2 adenovirus by electron nucroscopy, immunofluorescent antibody staining, and crosshemagglutinating-inhibition test.

Dogs experimental infected with parvovirus isolate or infected with both parvovinas and type 2 adenovinis isolates had the typical clinical signs and lesions of canine viral hemorrhagic gastroenteritis. Dogs infected with type 2 adenovirus isolate alone did not show any clinical sign.

Total of -137 canine serum samples were collected in Taiwan between 1979- 1982. Among them, 70% had positive hemagglutinating-inhibition antibody titers against canine parvovinas.
 

Keyword

adenovirusFDogs experimental thfectedFcanine parvovirus