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Publication Pathological Changes in Piglets Inoculated Intranasally With TNL Str...  

Update Date: [2013-11-05]

NO.: 20
 
Reportno.

AHRI report No.20

Topic

Pathological Changes in Piglets Inoculated Intranasally With TNL Strain of Pseudorabies Virus

Department

Taiwan Animal Health Research Institute

Author

S.Y. Yang;N.J. Li;J.S. Y.H. Yang;S.S. Lai

Summary

Y. Yang;N.J. Li;J.S. Y.H. Yang;S.S. Lai
Summary:Nonsuppurative menlingoencephalomyelitis with focal or diffuse gliosis, lymphocytic perivascular cuffing, neurophagia, and focal necrosis of lung were produced in piglets inoculated intransaally with 1 O”8.6 TCID5O TNL strain of pseudorabies virus (Pry). Eosinophilic intranuclear inclusion bodies were easily found in the necrotic areas of lung, but not found in the brain and spinal cord. The transmission of PrV from trigeminal and glossopharyngeal nerve to brain seemed more rapid than that from olfactory nerve. The pons was preferred for histopathologic examination. Intranasal inoculation of high dose of Pry could induce focal necrosis in visceral organs.

Keyword

Pseudorabies Virus pseudorabies virus PrV