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Publication The Development and Field Application of an Inactivated Infectious B...  

Update Date: [2013-11-11]

NO.: 28
 
Reportno.

AHRI report No.28

Topic

The Development and Field Application of an Inactivated Infectious Bovine Rhinotracheitis Vaccine

Department

Taiwan Animal Health Reseaxch lnstithte

Author Yong-Siu Lu, Yong-Lin Lee, Shu-Yen CM; Yung-Kung Liao, Mau-Jinn Kwan.g, ii or Dih-Fa Lin, and Hsiaizg-Jung Tsai
Summary

An inactivated inftious bovine thinotracheitis (BR) vaccine was develored using a kxal isolate as si virus. The virus was gopagai on Madin-Darby bovine kidney (MDBK) cell line, inactivatei with 0,2% formalin (vN) at 37°C for 10 hours, and then mixed with 10% aluminum plicGphae gel (vh). The inactivated BR vaccine was safe and effective. In 1987, tal of 6,473 ewere immunizx{ with the vaccine twice ata 4-weeks interval. No adverse reaction was oheerved in immunized cattle. The epizcx:*ic of BR in Taiwan was successfully cxntrollerl. The inactivati BR vaccine was stable and mnaintainerl its imnmunogenicity after ‘teing stxoi at 4°C for one year.

Keyword

Infectious bovine rhinotrecheitis, Vaccine